Paraferral 30 tablets based on Lactoferrin and Lactobacillus Paracasei

paraferral is a food supplement for the defense of the immune system based on Lactoferrin and Lactobacillus Paracasei, useful ingredients for supporting the immune system.

Available in packs of 30 tablets.

Directions
Lactobacillus Paracasei is a lactic acid bacterium belonging to the category of probiotics, i.e., microorganisms capable of resisting gastric juices and bringing benefits to the body.

Lactoferrin is a glycoprotein widely distributed in the body fluids of mammals, circulates mainly in blood plasma and is synthesized by epithelial cells.

Recent studies have highlighted the ability of probiotics to stimulate the production of antiviral antibodies and thus act in support of the immune system, intervening in particular in the fight against infections in the gastrointestinal and upper respiratory tract.

Knowing the importance of probiotics for intestinal balance and the role of the intestine for the functioning of the immune system and, also considering the link between the gastrointestinal system and possible respiratory manifestations, the role of this category of beneficial bacteria is evident.

Considering these aspects and adding them to the well-known antiviral, immunomodulatory and anti-inflammatory properties of Lactoferrin, the synergy between the latter and probiotics takes on a very interesting aspect.

Discovered for the first time around 1930 in the milk of mammals, its ability to transport iron within the cells of the human body and to control iron levels within the blood was immediately identified. It belongs to the transferrin family, molecules capable of binding to iron ions and numerous evidences attribute immunomodulatory, antiviral, antibacterial, antifungal, anti-thrombotic and antioxidant properties to Lactoferrin.

Lactoferrin's ability to chelate iron is very important and is supported by numerous studies indicating that iron chelators boast antiviral properties. For this reason, Lactoferrin exerts its immunomodulatory and anti-inflammatory activity by binding to certain receptors used by viruses, blocking their entry into the host cell.

By binding to iron, Lactoferrin regulates its homeostasis, after carrying it into the plasma and making it inaccessible to pathogens, interrupting their growth, inhibiting viral replication, oxidative stress and the synthesis of pro-inflammatory cytokines.

It is therefore understood that an excess of iron within cells causes oxidative stress following the increase in free radicals and promotes the replication of viruses, fungi and bacteria.

The ability of Lactoferrin to bind iron is therefore very important both for preventing and counteracting infections.

Lactoferrin synthesis decreases with age, and supplementation may therefore be necessary to maintain adequate levels of lactoferrin.

In the wake of numerous in vitro studies aimed at demonstrating the efficacy of Lactoferrin as an antiviral and immune system regulatory agent, a very recent Italian study published in the Journal of Clinical Medicine, conducted on a hundred asymptomatic, paucisymptomatic and moderately symptomatic patients with Covid-19, the oral administration of Lactoferrin has produced very promising results.

Posology
It is recommended to take one capsule a day on an empty stomach.

Average contents per daily dose 1 tablet:
- Lactobacillus Paracasei: 10 billion
- Lactoferrin 90%: 200 mg

Ingredients:
-Lactoferrin;
- Edible gelatine;
- Bulking agent: Microcrystalline cellulose;
- Lactobacillus Paracasei LPc 37;
- Anti-caking agent: mono and diglycerides of fatty acids.

LACTOSE-FREE, GLUTEN-FREE, GMO-FREE

What is lactoferrin
Discovered for the first time around 1930 in the milk of mammals, its ability to transport iron within the cells of the human body and to control iron levels within the blood was immediately identified. It belongs to the transferrin family, molecules capable of binding to iron ions and numerous evidences attribute immunomodulatory, antiviral, antibacterial, antifungal, anti-thrombotic and antioxidant properties to Lactoferrin.

Typical of milk, as the name suggests, lactoferrin is also present in various mucous secretions, such as tears and saliva.

More abundant in colostrum than transitional and maintenance milk, lactoferrin is also typical of neutrophil granulocytes, immune cells with defense functions against bacterial and fungal infections.

Lactoferrin is able to resist the proteolytic action that takes place in the digestive system and in particular in the stomach; for this reason, lactoferrin arrives unaltered in the intestine, carrying out its biological activity in the best possible way.